Description
Cefepime and Sulbactam powder for injection is a potent broad-spectrum antibiotic combination used to treat severe bacterial infections, including resistant strains. Cefepime (a fourth-gen cephalosporin) provides extended coverage, while Sulbactam enhances efficacy against beta-lactamase-producing bacteria. Ideal for hospital-acquired infections, pneumonia, UTIs, sepsis, and surgical prophylaxis.
These injections are manufactured and supplied by a well-renowned healthcare company, namely Khushru Medicare, under the dosage forms of 500 mg+250 mg, 1000 mg+500 mg, 2000 mg+1000 mg, respectively. They produce products under the compliance of ethical quality standards. They also offer various business and investment opportunities in PCD pharma franchise business.
Medical Benefits of Cefepime and Sulbactam Powder for Injection
The medicinal advantages provided by Cefepime and Sulbactam powder for Injection for the patients are mentioned below:
- Effective against Gram-positive & Gram-negative bacteria, including Pseudomonas aeruginosa.
- Sulbactam inhibits beta-lactamase enzymes, protecting Cefepime from degradation.
- Used for life-threatening infections (sepsis, ICU infections).
- Prevents/treats nosocomial (hospital-acquired) infections.
- Rapid therapeutic levels in blood for quick response.
- Effective in osteomyelitis, deep abscesses.
- Can be modified for renal impairment patients.
Storage Instructions for Cefepime and Sulbactam Powder for Injection
The ways to store Cefepime and Sulbactam powder for injection are given here:
- Store below 25°C (room temp), protected from light & moisture.
- Reconstituted solution: Use within 1 hour (or 24 hrs. if refrigerated).
- Do not freeze.
- Discard unused portions.
Directions for Using Cefepime and Sulbactam Powder for Injection
The directions in which the injection should be used are given below:
- IV infusion only (slow injection over 30 mins).
- Standard Dose: 1-2g Cefepime + 0.5-1g Sulbactam every 8-12 hrs. (varies by infection).
- Severe Infections: Up to 2g Cefepime + 1g Sulbactam every 8 hrs.
- Renal Dose Adjustment: Required for CrCl <50 mL/min.
- Reconstitute with sterile water/NS; use immediately.
Precautions for Using Cefepime and Sulbactam Powder for Injection
The safety measures for using Cefepime and Sulbactam powder for injection are explained below:
- Do not use if allergic to cephalosporins or penicillin’s due to the risk of severe allergic reactions.
- Monitor kidney function regularly, as dosage adjustment is required for patients with renal impairment.
- Avoid in patients with bleeding disorders or those on anticoagulants, as it may increase bleeding risk.
- Do not consume alcohol during treatment as it may cause disulfiram-like reactions.
- This medication is not effective against viral infections such as colds or flu.
- Pregnant women should use it only if needed after consulting a doctor.
- Complete the full prescribed course to prevent antibiotic resistance, even if symptoms improve earlier.
Side Effects of Cefepime and Sulbactam Powder for Injection
The negative effects patients can face while using Cefepime and Sulbactam powder for injection are:
- Diarrhea
- Injection site reaction
- Injection site pain
- Injection site inflammation
- Allergic reaction
- Rash
Frequently Asked Questions (FAQs)
Can Cefepime and Sulbactam Powder for Injection cause allergic reactions?
Yes, Cefepime and Sulbactam Powder for Injection may cause severe allergic reactions, especially in patients allergic to penicillin or other cephalosporins.
How long should treatment with Cefepime and Sulbactam Powder for Injection last?
Treatment with Cefepime and Sulbactam Powder for Injection typically lasts 7 to 14 days, depending on the infection severity.
What should I do if I miss a dose of Cefepime and Sulbactam Powder for Injection?
If you miss a dose of Cefepime and Sulbactam Powder for Injection, contact your healthcare provider immediately, as it is typically administered in hospital settings.
Why is Sulbactam combined with Cefepime in Cefepime and Sulbactam Powder for Injection?
Sulbactam is combined with Cefepime in Cefepime and Sulbactam Powder for Injection to overcome bacterial resistance by inhibiting beta-lactamase enzymes.